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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG9
All Species:
19.39
Human Site:
S450
Identified Species:
38.79
UniProt:
Q9H0W8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0W8
NP_061981.2
520
57651
S450
P
P
R
A
G
P
G
S
S
P
L
F
S
L
L
Chimpanzee
Pan troglodytes
XP_001158051
495
54769
E425
P
P
D
F
L
D
S
E
V
N
L
F
L
V
P
Rhesus Macaque
Macaca mulatta
XP_001106959
520
57618
S450
P
P
R
A
G
P
S
S
S
P
L
F
S
L
L
Dog
Lupus familis
XP_533650
520
57589
S450
P
P
R
A
G
P
G
S
S
P
L
F
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB90
520
57602
S450
P
P
R
A
G
P
G
S
S
P
L
F
S
L
L
Rat
Rattus norvegicus
Q5PQS6
520
57614
S450
P
P
R
A
G
P
G
S
S
P
L
F
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515769
130
14079
Q61
T
Q
P
V
Y
Q
I
Q
N
R
G
M
G
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q05AW9
508
56581
G438
I
S
R
A
G
T
S
G
I
P
L
F
S
L
L
Zebra Danio
Brachydanio rerio
XP_001923815
503
56076
G433
E
D
A
L
T
R
A
G
P
P
L
F
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395241
359
40784
S290
F
Y
T
K
L
F
S
S
S
R
L
Q
I
H
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780386
532
57732
C462
A
E
K
E
S
K
T
C
V
L
Q
F
V
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143814
423
45897
T354
L
R
G
H
D
D
S
T
K
F
E
Y
G
T
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.2
98.2
N.A.
97.3
96.9
N.A.
21.9
N.A.
74.8
72.6
N.A.
N.A.
29.4
N.A.
37.4
Protein Similarity:
100
95.1
99.6
98.6
N.A.
98.4
98.4
N.A.
22.5
N.A.
85.5
85.3
N.A.
N.A.
44.8
N.A.
53.2
P-Site Identity:
100
26.6
93.3
100
N.A.
100
100
N.A.
0
N.A.
60
40
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
33.3
93.3
100
N.A.
100
100
N.A.
6.6
N.A.
60
40
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
39.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
50
0
0
9
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% C
% Asp:
0
9
9
0
9
17
0
0
0
0
0
0
0
0
9
% D
% Glu:
9
9
0
9
0
0
0
9
0
0
9
0
0
0
0
% E
% Phe:
9
0
0
9
0
9
0
0
0
9
0
75
0
0
0
% F
% Gly:
0
0
9
0
50
0
34
17
0
0
9
0
17
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% I
% Lys:
0
0
9
9
0
9
0
0
9
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
17
0
0
0
0
9
75
0
9
59
59
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
50
50
9
0
0
42
0
0
9
59
0
0
0
9
9
% P
% Gln:
0
9
0
0
0
9
0
9
0
0
9
9
0
0
0
% Q
% Arg:
0
9
50
0
0
9
0
0
0
17
0
0
0
0
0
% R
% Ser:
0
9
0
0
9
0
42
50
50
0
0
0
59
0
9
% S
% Thr:
9
0
9
0
9
9
9
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
17
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
0
0
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _